Soft drinks can aggravate the clinical manifestations of renal injury acute kidney injury
Soft drinks can aggravate the clinical manifestations of renal injury acute kidney injury
Recently, there have been repeated reports that repetitive dehydration caused by a high temperature environment is associated with an increased risk of chronic kidney damage. A recent study published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology showed that dehydration and soft drink supplementation can increase dehydration and kidney damage.
Researchers exposed mice to high temperature (36°C) for 1 hour/24 hours, followed by clear water (W), 11% fructose-glucose solution (FG, typical of soft drinks), or stevia water (ST) 2 hour. Fructose and glucose - naturally present in food - are sweet additives in soft drinks. Stevia is a plant-derived sugar substitute that does not contain calories. After 4 weeks, blood and urine specimens were collected and evaluated for oxidative stress, inflammation and damage in the kidneys.
The results showed that mice taking 11% fructose glucose solution had higher degrees of dehydration and kidney damage than mice taking clear water and stevia water.
The researchers said, "The results of this study emphasize that people in daily life should be highly valued after taking dehydration and taking soft drinks to quench their thirst, especially for adolescents and young adults, and should be alert to potential risks."
The research team is working on a drug research and development patent that will prevent kidney damage by blocking fructose metabolism.
Kidney injury
The kidney is located behind the retroperitoneum and is located deep. It is usually not easy to damage, but it is often caused by open wounds due to knife stabs and gunshot wounds. Can also be due to a direct blow to the waist or upper abdomen, or intense oscillations cause damage to the renal parenchyma, known as closed injury. Due to the abundant blood supply to the kidneys, once the injury is easily caused by bleeding and urine extravasation into the tissue, shock and infection occur. Kidney injury is more common in men aged 20-40. It accounts for 3% of hospitalized trauma patients and 8-10% of abdominal injuries. 6-14% of abdominal puncture wounds can damage the kidneys.
Clinical manifestations
1. Shock.
2. Hematuria.
3. Nephritic pain, tenderness and muscle tension.
4. Waist mass.
5. Chills and fever.
6. Open wounds have blood and urine flow out of the wound.
Diagnose based on
1. History of waist or upper abdominal trauma.
2. Shock.
3. Hematuria, urine has a large number of red blood cells.
4. Waist pain and mass.
5. Intravenous pyelography or CT or MRI showed perirenal hematoma, contrast agent extravasation, cortical laceration or renal pedicle injury.
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