Alcohol abuse prone to alcoholic liver disease
2018-05-25 00:20:37
According to scientists, drinking 80-150 grams of white wine a day can cause liver damage for 5 consecutive years. Drink plenty of liquor for more than 20 years, 40% -50% of people will develop liver cirrhosis, daily consumption of 200 grams of white wine for 10 years can appear fatty liver.
Alcohol damage to the liver is mainly caused by ethanol itself and its metabolite acetaldehyde. The large accumulation of ethanol and acetaldehyde will reduce the bioactivity of various enzymes in hepatocytes, affect the normal metabolism of sugar, fat and protein, change the structure of cell membranes, cause hepatocyte destruction, fat deposition, and even liver fibrosis and liver cirrhosis. In addition, acetaldehyde is a vasoactive substance that can cause telangiectasias. Some people can not quickly convert acetaldehyde to acetic acid because of the lack of acetaldehyde metabolic enzymes in the body. Therefore, after drinking a small amount of white wine, skin flushing on the cheeks, neck, and chest can occur. In severe cases, palpitation, shortness of breath or depression can occur.
Mild alcoholic liver disease without symptoms, severe loss of appetite, nausea, abdominal swelling, hepatomegaly, jaundice or ascites and other clinical manifestations. Laboratory tests can show abnormal liver function in different degrees, among which aspartate aminotransferase (AST) and glutamyl transferase (GGT) are more prominent.
The purpose of treating alcoholic liver disease is to relieve the inflammatory reaction of liver cells, reduce the deposition of hepatic fat, prevent the development of hepatic fibrosis, and improve malnutrition. Patients must strictly abstain from alcohol, fundamentally remove the cause, and at the same time can be prescribed by doctors, choose some liver protection drugs. For healthy people, it is necessary to drink white wine in moderation, and take care of the cup to prevent it.
Alcohol damage to the liver is mainly caused by ethanol itself and its metabolite acetaldehyde. The large accumulation of ethanol and acetaldehyde will reduce the bioactivity of various enzymes in hepatocytes, affect the normal metabolism of sugar, fat and protein, change the structure of cell membranes, cause hepatocyte destruction, fat deposition, and even liver fibrosis and liver cirrhosis. In addition, acetaldehyde is a vasoactive substance that can cause telangiectasias. Some people can not quickly convert acetaldehyde to acetic acid because of the lack of acetaldehyde metabolic enzymes in the body. Therefore, after drinking a small amount of white wine, skin flushing on the cheeks, neck, and chest can occur. In severe cases, palpitation, shortness of breath or depression can occur.
Mild alcoholic liver disease without symptoms, severe loss of appetite, nausea, abdominal swelling, hepatomegaly, jaundice or ascites and other clinical manifestations. Laboratory tests can show abnormal liver function in different degrees, among which aspartate aminotransferase (AST) and glutamyl transferase (GGT) are more prominent.
The purpose of treating alcoholic liver disease is to relieve the inflammatory reaction of liver cells, reduce the deposition of hepatic fat, prevent the development of hepatic fibrosis, and improve malnutrition. Patients must strictly abstain from alcohol, fundamentally remove the cause, and at the same time can be prescribed by doctors, choose some liver protection drugs. For healthy people, it is necessary to drink white wine in moderation, and take care of the cup to prevent it.