Analysis: Broad market for rheumatoid arthritis biologics

Business Club November 17th, organized by the Chinese Medical Doctor Association, sponsored by the Shanghai Medical Association Rheumatology Professional Committee and co-organized by Shanghai CITIC Guojian Pharmaceutical Co., Ltd., “as always, care for health” start up. The campaign aims to promote awareness of rheumatic diseases throughout the society through expert consultations, health education, and care for patients, and to arouse people's attention to such diseases.

In fact, the number of rheumatic immune diseases in China is increasing year by year, the prevalence of rheumatoid arthritis is about 0.3% to 0.5%, and the prevalence of ankylosing spondylitis is about 0.3%. Studies have shown that 75% of patients with rheumatoid arthritis can have bone destruction within 2 years of onset. Up to 80% of patients experience disability after 20 years of illness. One-third of patients with work ability are affected. After 2 years of loss of working ability. In addition, rheumatism can lead to increased mortality compared to the general population. To this end, experts emphasized that rheumatism should be diagnosed and treated early.

In common drug treatment programs, non-steroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, and other disease-relief drugs can be used to relieve pain and relieve various symptoms. However, clinical observations have found that even if traditional medicines are used continuously for 5 to 10 years, the disease activity indicators can be improved, and the joint destruction can still not be effectively controlled. The emergence of biological agents will help improve this situation. Prof. Bao Chunde of Renji Hospital pointed out that biological agents (such as Yisaipu) are antagonists against specific pathogenic target molecules. They can block the occurrence and development of disease factors through molecular targeting and break the original drugs only to help patients. Relieving symptoms does not stop the progression of the disease. If used early in the disease, it will help relieve the symptoms and block or even reverse the condition.