Technical points for using a long oil cycle

1, to prevent the body oil spill oil leakage on the one hand will cause a waste of oil, on the other hand, the lower oil surface of the pool bottom will inevitably cause poor lubrication, leakage should be immediately identified, drain.
2. Keep the crankcase of the engine well ventilated. As the engine works, part of the exhaust gas enters the crankcase along the piston and the cylinder wall. The high-temperature and high-pressure exhaust gas reacts with the engine oil to accelerate the oxidative deterioration and formation of gum and coke. Therefore, worn pistons, liners, or valve guide assemblies must be replaced in time to reduce exhaust squats. At the same time, we must always check whether the vents are unblocked, and ensure that the exhaust gas in the crankcase can be discharged in time.
3, to prevent the fuel from leaking into the oil pan due to the fuel pan will dilute the oil, so that the viscosity of the oil drop, prematurely lose the role of lubrication, so the diesel fuel injection pump pressure is sufficient, the atomizer atomization is good, the throttle control is reasonable Make sure the fuel burns completely.
4, to avoid the engine working water-cooled engine under high temperature conditions, the general requirements of the normal operating temperature is 80-95 °C, the temperature is too high will make the engine oil thin, and accelerate engine oil deterioration. Therefore, if it is found that the water temperature is too high, it should be immediately stopped and checked before troubleshooting.
5, regular maintenance of oil filter because of prolonged use, will cause filter filter plugging, severe blockage will force the safety valve to open, after the safety valve is opened, the unfiltered oil directly into the movement of the auxiliary surface, one to exacerbate the parts Wear, and secondly cause the accumulation of impurities in the oil pan, eventually accelerating oil failure. Therefore, the filter must be cleaned regularly and the filter element must be replaced.
6. Regular cleaning of the oil sump of the oil sump will inevitably be contaminated by the exhaust gas and produce many harmful substances after use for a period of time. If the residual oil in the engine is mixed with the new oil, the used oil will cause rot to the new engine oil. Therefore, the oil pan, main oil passage and oil filter must be thoroughly cleaned when changing the oil. The method for cleaning the waste oil in the engine body is: after shutting down, remove the hot oil and add the same amount of clean diesel oil. After allowing the engine to run idly for 3-5 minutes, the net oil can be released.
7. Select the oil of the right grade to select the engine oil according to the engine's instructions, and select the appropriate engine oil according to the changes of the season and the change of the machine's use location. Before replacing the oil, the lubricating oil tract should be cleaned in the same way as the scavenged oil in the machine body. The publication of this manuscript by this site is for the purpose of conveying more information and does not imply endorsement of its views or the authenticity of its contents.

What are peptides?

Peptides are naturally occurring biological molecules. Peptides are found in all living organisms and play a key role in all manner of biological activity. Like proteins, peptides are formed (synthesized) naturally from transcription of a sequence of the genetic code, DNA. Transcription is the biological process of copying a specific DNA gene sequence into a messenger molecule, mRNA, which then carries the code for a given peptide or protein. Reading from the mRNA, a chain of amino acids is joined together by peptide bonds to form a single molecule.

There are 20 naturally-occurring amino acids and, like letters into words, they can be combined into an immense variety of different molecules. When a molecule consists of 2-50 amino acids it is called a peptide, whereas a larger chain of > 50 amino acids generally is referred to as a protein.

Peptides are in every cell and tissue in the body

In the human body, peptides are found in every cell and tissue and perform a wide range of essential functions. Maintenance of appropriate concentration and activity levels of peptides is necessary to achieve homeostasis and maintain health.

The function that a peptide carries out is dependent on the types of amino acids involved in the chain and their sequence, as well as the specific shape of the peptide. Peptides often act as hormones and thus constitute biologic messengers carrying information from one tissue through the blood to another. Two common classes of hormones are peptide and steroid hormones. Peptide hormones are produced in glands, and a number of other tissues including the stomach, the intestine and the brain. Examples of peptide hormones are those involved in blood glucose regulation, including insulin, glucagon-like-peptide 1 (GLP-1) and glucagon, and those regulating appetite, including ghrelin.


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Peptides primarily creates a biological effect by binding to cell surface receptors

For a peptide to exert its effect, it needs to bind to a receptor specific for that peptide and which is located in the membrane of relevant cells. A receptor penetrates the cell membrane and consists of an extracellular domain where the peptide binds, and an intracellular domain through which the peptide exerts its function upon binding and activation of the receptor. An example is the GLP-1 receptor, which is located on beta cells in the pancreas. Upon activation of the receptor by natural GLP-1 or a peptide analog (a synthesized molecule mimicking the effect of natural GLP-1, such as our lixisenatide), the cell is stimulated through a series of biological events to release insulin.

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