US scientists invent new instruments for bacterial membrane testing
Release date: 2007-08-17
US scientists have invented a new instrument for the detection of bacterial membranes. The cross-flow analysis device jointly developed by the students of the University of North Arizona and the University of Maryland has discovered the biofilm-specific antibodies in the patient's body by combining the biofilm-specific proteins with antibodies. The principle is similar to detecting a streptococcal infection. This will help medical staff diagnose biofilm infectious diseases and implement effective treatment as soon as possible.
Most of the bacteria exist in the form of "micro-cloning". The bacteria itself occupy less than one-third of the volume in each "micro-cloning", and the remaining space is secreted by bacteria called "extracellular matrix". Substance of matter, this viscous substance binds thousands of bacterial microclone together to form a biofilm.
About 70% of bacterial infections are caused by bacterial biofilms. Bacterial biofilms are highly resistant to antibiotics and host immune defense mechanisms. Once a biofilm is formed at a site of infection, even a 100-fold dose of a normal dose is not easily cured, which is important for chronic and refractory infectious diseases. one of the reasons. According to data from the US Centers for Disease Control and Prevention, the annual cost of treating such infectious diseases in the United States is about $5 billion.
Jeff Laide, from the Center for Microbial Genetics at the University of Northern Arizona, said: "In the past, medical workers did not have an effective way to diagnose these infectious diseases, thus delaying the treatment of patients. Now, the problem is expected to be solved." Researchers are working hard to negotiate the details of the instrument and look for companies interested in registering the technology to mass produce the instrument, making it widely available as a medical device. —— Information from: China Medical Device Network
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